Effects on Uric Acid Metabolism of the Drugs except the Antihyperuricemics

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Effects on Uric Acid Metabolism of the Drugs except the Antihyperuricemics

The normal adult male has a total body urate pool of approximately 1200 mg. Daily turnover of about 60 percent of the urate pool is achieved by balanced production and elimination of uric acid. About one-third of the human uric acid is derived from diet, while two-thirds is generated endogenously. The major site of purine synthesis is in the liver. The synthesis of uric acid occurs along two pa...

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ژورنال

عنوان ژورنال: Journal of Bioequivalence & Bioavailability

سال: 2014

ISSN: 0975-0851

DOI: 10.4172/jbb.1000173